Institutional Review Board
- The Institutional Review Board (IRB) is a committee that reviews and supervises human-subject research, embryonic stem cell research, and research involving human-derived materials conducted by researchers affiliated with KAIST.
- Scope of IRB review
- General ethical considerations for human-subject research in research projects specified by law among projects conducted at KAIST
- Ethical and scientific validity of research proposals, including human-subject research
- Verification of proper procedures for obtaining consent from research subjects and sample providers
- Safety measures and information protection measures for research subjects, sample providers, and other subjects of genetic information
- Matters urgently raised by the president as posing or likely to pose a significant risk to bioethics or safety due to human-subject research conducted by KAIST
- Other matters based on legal provisions or raised by the chair of IRB
- Human-subject research :
Research involving direct physical intervention with individuals, studies conducted through interaction such as communication or interpersonal contact, and research utilizing personally identifiable information
- Human-derived material research :
Research involving the direct investigation and analysis of tissues, cells, body fluids, and other human components collected or obtained from the human body, or those separated from them, including serum, plasma, chromosomes, DNA (deoxyribonucleic acid), RNA (ribonucleic acid), proteins, etc.
- Human embryonic stem cell research :
Research utilizing cell lines (registered with the Ministry of Health and Welfare) derived from embryos, somatic cell nuclear transfer embryos, or single-cell embryos, and capable of continuous proliferation under suitable culture conditions and differentiation into various cell types
- Review application: Submit documents within the period specified in the portal announcement or e-mail
- Required documents
Classification | Required documents | |
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General |
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Additional (where applicable) |
Human-subject research |
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Human-derived material research |
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Human embryonic stem cell research |
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Classification | Required documents |
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Change of research plan | [Form 10] Application for change of research plan (Where applicable) Other supporting documents |
Continuing review |
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Classification | Required documents |
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Review exemption confirmation |
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Human-subject research | Human-derived material research |
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Eligibility for review exemption to be confirmed by IRB, not researchers.
Classification | Required documents |
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Re-review |
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Early closure report review |
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Closure and results review |
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Classification | Review details | Review cycle |
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Expedited review |
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1 month |
Regular review |
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2 months |
Review type to be determined by IRB.
- The IRB follows the principle of pre-review. Researchers must apply for review before initiating any research involving human subjects.
- The principal investigator and participating researchers must complete bioethics education before submitting an IRB review application.
- Any principal investigator intending to provide human-derived materials or personal information collected through research to a third party must obtain IRB approval for the provision of human-derived materials or personal information.
- Research approved by the IRB should only proceed within the approved scope, and any necessary changes must be submitted for review and approval. The research should then proceed with the plan reflecting the approved modifications.
- Projects confirmed to be exempt from review are prohibited from modifying their research plans.
- The final report must be submitted to the IRB for both approved projects and projects confirmed to be exempt from review upon completion of the research.
- Bioethics and Safety Act, Ministry of Health and Welfare
- IRB Information Portal http://irb.or.kr/
- Standard Operating Guidelines of Bioethics Committee